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Their discussion of circumcision pp begins with a claim that because only 16 actually 9 according to their own table of the men aged were intact compared to 26 of the 81 older men , there was "a medical trend toward urging routine circumcision of the newborn male infant. They also assume their sample of volunteers who were comfortable having sex in front of the experimenters was representative of the whole population of the US, and the 35 intact ones representative of all intact men. They continue in prose famous for its obscurity and ugliness: The phallic fallacy that the uncircumcised male can establish ejaculatory control more effectively than his circumcised counterpart was accepted almost universally as biologic fact by both circumcised and uncircumcised male study subjects. Magazines like Penthouse were suggesting that intact men with premature ejaculation might get circumcised to prevent it. All involved in this fallacy seem to have been unaware that the foreskin can retract.
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It inhibits nerve transmission in the brain, calming nervous activity. As a supplement it is sold and promoted for these neurotransmitter effects as a natural tranquilizer. It is also touted as increasing Human Growth Hormone levels and is popular among body builders. The published research supporting any of these promotional claims is weak. Current medical opinion says that GABA taken as a supplement does not reach the brain and has no effect or benefit aside from being a benign placebo.
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Function[ edit ] TRPV1 is a nonselective cation channel that may be activated by a wide variety of exogenous and endogenous physical and chemical stimuli. The best-known activators of TRPV1 are: Its endogenous activators include: TRPV1 receptors are found mainly in the nociceptive neurons of the peripheral nervous system , but they have also been described in many other tissues, including the central nervous system.
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